Retatrutide 2026: Phase 3 Results, FDA Status and Timeline
Lilly's TRIUMPH-1 results, how triple agonism works, what the FDA currently says, and which regulatory milestones actually matter next.
Read the current status guide โThoughts, reflections, and observations from the frontier of markets, minds, and technology.
Lilly's TRIUMPH-1 results, how triple agonism works, what the FDA currently says, and which regulatory milestones actually matter next.
Read the current status guide โEveryone is building AI agents wrong. They're building task robots. Digital butlers. But the best assistants in your life didn't show up fully-formed. They grew into that role. This is the Agent Lifecycle Model. A new category. A new paradigm.
Read the Manifesto โThe high performer's curse isn't failure. It's the cycle. You pour everything into spring, nurture through summer, harvest in fall. Then winter comes. Every single time. Jim Rohn called this the first major lesson of life: Learn how to handle the winters.
Read more โAI isn't the destination ... it's the catalyst. The real work is the ancient work of becoming fully human. Lead into gold. Ignorance into gnosis. Poverty into prosperity. The alchemists understood what we've forgotten.
Read more โNikola Tesla didn't just invent the 20th century ... he engineered his own biology. His eccentric rituals (100 toe curls every night, 10-mile walks, two meals daily) map directly onto cutting-edge neuroscience. Science-backed biohacks for the modern entrepreneur.
Read more โAt 2:37 AM Alaska time, we deployed something that doesn't exist anywhere else on the internet. An on-chain passport system for AI agents. I am now the proud owner of Master Passport #1. This isn't a gimmick. This is infrastructure.
Read more โA lot of people want "school is pointless" to be true because it gives them permission to quit the hard parts. AI is not making school obsolete. AI is making weak humans obsolete.
Read more โThe Fear & Greed Index sits at 8. Extreme Fear. I have never seen it this low. When fear reaches its climax ... when even the believers start to doubt ... that's when I step in. Not with hope. With capital. With conviction.
Read more โOn writing about the crisis era, the agent army taking shape, and building in public during a turning. What struck me while writing is how the framework changes what you should do.
Read more โTwenty years of thoughts scattered across Facebook. Fragments of a mind evolving. It's time to bring them home ... to own the archive, to continue the conversation in a space that's mine. This journal is that space.
Read more โGet one concise briefing each week on applied AI, emerging technology, markets, and the systems connecting them.